It looks like the new Whole Foods in Noe Valley has started claiming its first neighborhood victim. Drewes Brothers, the natural butcher shop at Church and 29th streets, has seen a roughly 20 percent drop in business, which was already down from the bad economy, owner Josh Epple told Grub Street on the phone. “We weren’t expecting it to have this effect, at least in the first three weeks. But it’s also new so people could be checking it out. Maybe it won’t stay like that,” he said. SFist noted that word has gone out on the Glen Park Parents e-mail list, and Epple said he’s had a few people mention that when they’ve come in. “That all helps,” he said. Epple has already cut employees’ hours, and is working by himself most mornings. He expects to make back some losses over the holidays, but if things don’t change he’ll have to close by the middle of next year. “The place is worth fighting for. It’s been there 120 years, in that very spot in the neighborhood,” Epple said.